Proteins are complex, organic compounds composed of many amino acids linked together through peptide bonds and cross-linked between chains by sulfhydryl bonds, hydrogen bonds and van der Waals forces. There is a greater diversity of chemical composition in proteins than in any other group of biologically active compounds. The proteins in the various animal and plant cells confer on these tissues their biological specificity.Image

Proteins can be classified as:

(a) Simple proteins. On hydrolysis they yield only the amino acids and occasional small carbohydrate compounds. Examples are: albumins, globulins, glutelins, albuminoids, histones and protamines.

(b) Conjugated proteins. These are simple proteins combined with some non-protein material in the body. Examples are: nucleoproteins, glycoproteins, phosphoproteins, haemoglobins and lecithoproteins.

(c) Derived proteins. These are proteins derived from simple or conjugated proteins by physical or chemical means. Examples are: denatured proteins and peptides.

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 Structure

The potential configuration of protein molecules is so complex that many types of protein molecules can be constructed and are found in biological materials with different physical characteristics. Globular proteins are found in blood and tissue fluids in amorphous globular form with very thin or non-existent membranes. Collagenous proteins are found in connective tissue such as skin or cell membranes. Fibrous proteins are found in hair, muscle and connective tissue. Crystalline proteins are exemplified by the lens of the eye and similar tissues. Enzymes are proteins with specific chemical functions and mediate most of the physiological processes of life. Several small polypeptides act as hormones in tissue systems controlling different chemical or physiological processes. Muscle protein is made of several forms of polypeptides that allow muscular contraction and relaxation for physical movement.

 Structure

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Essential amino acids
Humans can produce 10 of the 20 amino acids. The others must be supplied in the food. Failure to obtain enough of even 1 of the 10 essential amino acids, those that we cannot make, results in degradation of the body’s proteins—muscle and so forth—to obtain the one amino acid that is needed. Unlike fat and starch, the human body does not store excess amino acids for later use—the amino acids must be in the food every day.

The 10 amino acids that we can produce are alanine, asparagine, aspartic acid, cysteine, glutamic acid, glutamine, glycine, proline, serine and tyrosine. Tyrosine is produced from phenylalanine, so if the diet is deficient in phenylalanine, tyrosine will be required as well. The essential amino acids are arginine (required for the young, but not for adults), histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine. These amino acids are required in the diet. Plants, of course, must be able to make all the amino acids. Humans, on the other hand, do not have all the the enzymes required for the biosynthesis of all of the amino acids.

proteins!!! yummy in my tummy

1)__________ are macromolecules that are made up of repeated molecules of glucose.

2)At physiological pH, amino acids are zwitterions. Which of the following is a zwitterion?

A. A
B. B
C. C
D. D

3)

Collagen, a major component of skin and bone, is a fibrous protein with repeating units of Pro-Gly-X or Hyp-Gly-X. Collagen has strength because the structure is:

A.         Web like

B.         Three interlaced helices forming a rope

C.         An a-helix

D.         A b-sheet

E.         A b-barrel

4)

Proteins must fold into their final structures to be functional. Which of the following statements are not true?

A.         Protein tertiary structure is determined by the primary sequence.

B.         Hydrophobic amino acids are buried in the interior.

C.         Structural motifs such as aa or bb act as seeds around which the rest of the protein folds.

D.         Helper proteins called chaperones may assist protein folding.

E.         Folding begins with disulfide bond formation.

5)

Triacylglycerols are a cellular metabolic fuel. Which of the following are true of triacylglycerols?

A.            They are polar, hydrophobic molecules.

B.            Most triacylglycerols have three fatty acid groups that are identical.

C.            They should be completely eliminated from the human diet.

D.            Triacylglycerols from animals are solids at room temperature while those from plants are liquid.

some easy questions

hi guys , wow well these last few weeks has been hectic . our last biochem tutorial was soo much fun . our group got full marks 🙂 these tutorial sessions have been soooo helpful to me . not only is it so much fun its very educational and enticing . mr mathews really knows to make learning fun wowwwww . thanx sir